Oxidative stress (free radicals) are a contributing factor in all diseases
A recent US Patent application (May 22, 2104) for Fullerenes or Carbon 60 claims that oxidative stress from free radicals (or Reactive Oxygen Species (ROS)) is a contributing factor in all diseases. WOW I've never seen such a wide ranging claim-Walter Derzko, Toronto.
Re: Fullerene and its use to maintain good health and to prolong the expected lifespan of mammals
...This is from a US patent application of fullerenes... or Carbon--60 partially dissolved in olive oil.
However, Ukrainian-produced hydrated fullerenes (C-60 HyFN's) from Kharkiv are much superior. (see US patent application http://www.freepatentsonline.com/y2014/0079746.html They don’t need an olive oil carrier, which takes two months to dissolve. They are water-soluble. Ukrainian scientists were the only ones who discovered how to make them water-soluble, without increasing its toxicity, like most functionalized fullerene derivatives, which are toxic. Pristine Carbon-60 is a natural product found in abundance in nature, safe and the highest antioxidant in the world and it scavenges/neutralizes excess free radicals in your body. It was approved by the Ukrainian Ministry of Health in 2010 as a “dietary supplement” after 18 years of clinical and preclinical studies—Walter Derzko.
Hydrated Fullerenes or Carbon-60, the highest anti-oxidant in the world is better than traditional botanical anti-oxidants such as blueberry extract or green tea extract, because it does not get immediately metabolized by gut bacteria, before it gets a chance to act as an anti-oxidant. That’s why we see differing ORAC test values for traditional botanical anti-oxidants under in vivo and in vitro conditions. Hydrated Fullerenes do not get metabolized by gut bacteria.
KEY QUOTE: WOW “all diseases caused by free radicals” I’ve never seen any scientist make this wide reaching claim, directly.--Walter Derzko
“Considerable evidence supports the view that oxidative damage involving free radicals occurs in most, if not all, human diseases. Oxidative stress is now recognized as an important contributor to the development of many human diseases including liver fibrosis, ischemia-reperfusion, atherosclerosis, neurodegenerative disease and age-related cancer as well as to process of ageing. Thus antioxidants and systems that can protect against oxidative stress are needed to maintain health. A large body of scientific evidence supports that oxidative stress is directly responsible for aging.”
From the Patent Application (Fullerene and its use to maintain good health and to prolong the expected lifespan of mammals) has a good description of oxidative stress and free radicals:
“2. Description of Related Art
Free radicals, such as oxygen radicals and other reactive oxygen/nitrogen/chlorine species (hydroxyl, nitric oxide radicals), are constantly formed in vivo. Some of these molecules are physiologically useful, but they can also result in pathological oxidative stress to cells and tissues. Endogenous defences include both antioxidants and repairing systems. However, excess production of free radicals, their production in inappropriate relative amounts or deficiencies in endogenous defences can have deleterious effects. Free radicals can cause oxidative damage to lipids, DNA, bio molecules, rises in the concentration of intracellular calcium, as well as activation of proteases, nucleases and protein kinases. Considerable evidence supports the view that oxidative damage involving free radicals occurs in most, if not all, human diseases. Oxidative stress is now recognized as an important contributor to the development of many human diseases including liver fibrosis, ischemia-reperfusion, atherosclerosis, neurodegenerative disease and age-related cancer as well as to process of ageing. Thus antioxidants and systems that can protect against oxidative stress are needed to maintain health. A large body of scientific evidence supports that oxidative stress is directly responsible for aging (Aging Cell. 2009, 8(3):258-69) and an array of neuropathology conditions (Nutrition 2010, 26:595-603. Neurochem Res. 2007, 32:757-73). The free radical theory of aging proposes that the organism is unable to repair all of them and that, with time, unrepaired damages accumulate and put the organism at risk: in other words, free radicals provoke aging and death (FEBS Letters 2009, 498: 183-186. J. Neurochem. 2009, 108:1251-65). Antioxidants are the substances able to react with free radicals and to protect the body from the damage caused by these molecules (Ital J Biochem. 2006, 55:263-282). In particular, consumption in excess of some foods which are rich sources of antioxidants is considered to promote good health and longevity. It is now believed that the maintenance of redox balance within the body can forestall aging and promote good health and longevity..